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Conjugation with gold nanoparticles improves the stability of the KT2 peptide and maintains its anticancer properties
One of the major weaknesses of therapeutic peptides is their sensitivity to degradation by proteolytic enzymes in vivo. Gold nanoparticles (GNPs) are a good carrier for therapeutic peptides to improve their stability and cellular uptake in vitro and in vivo. We conjugated the anticancer KT2 peptide...
Autores principales: | Maraming, Pornsuda, Daduang, Jureerut, Kah, James Chen Yong |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
The Royal Society of Chemistry
2021
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8978663/ https://www.ncbi.nlm.nih.gov/pubmed/35424498 http://dx.doi.org/10.1039/d1ra05980g |
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