Investigating natural compounds against oncogenic RET tyrosine kinase using pharmacoinformatic approaches for cancer therapeutics

Rearranged during transfection (RET) tyrosine kinase is a transmembrane receptor tyrosine kinase regulating vital aspects of cellular proliferation, differentiation, and survival. An outstanding challenge in designing protein kinase inhibitors is due to the development of drug resistance. The “gain...

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Detalles Bibliográficos
Autores principales: Parate, Shraddha, Kumar, Vikas, Chan Hong, Jong, Lee, Keun Woo
Formato: Online Artículo Texto
Lenguaje:English
Publicado: The Royal Society of Chemistry 2022
Materias:
Chemistry
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8978841/
https://www.ncbi.nlm.nih.gov/pubmed/35425116
http://dx.doi.org/10.1039/d1ra07328a

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8978841/
https://www.ncbi.nlm.nih.gov/pubmed/35425116
http://dx.doi.org/10.1039/d1ra07328a

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