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CD169-mediated restrictive SARS-CoV-2 infection of macrophages induces pro-inflammatory responses

Exacerbated and persistent innate immune response marked by pro-inflammatory cytokine expression is thought to be a major driver of chronic COVID-19 pathology. Although macrophages are not the primary target cells of SARS-CoV-2 infection in humans, viral RNA and antigens in activated monocytes and m...

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Detalles Bibliográficos
Autores principales: Jalloh, Sallieu, Olejnik, Judith, Berrigan, Jacob, Nisa, Annuurun, Suder, Ellen L, Akiyama, Hisashi, Lei, Maohua, Tyagi, Sanjay, Bushkin, Yuri, Mühlberger, Elke, Gummuluru, Suryaram
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Cold Spring Harbor Laboratory 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8978933/
https://www.ncbi.nlm.nih.gov/pubmed/35378756
http://dx.doi.org/10.1101/2022.03.29.486190