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Repeated ethanol exposure and withdrawal alters ACE2 expression in discrete brain regions: Implications for SARS-CoV-2 infection
Emerging evidence suggests that people with alcohol use disorders are at higher risk for SARS-CoV-2. SARS-CoV-2 engages angiotensin-converting enzyme 2 (ACE2) and transmembrane serine protease 2 (TMPRSS2) receptors for cellular entry. While ACE2 and TMPRSS2 genes are upregulated in the cortex of alc...
Autores principales: | Balasubramanian, Nagalakshmi, James, Thomas D, Pushpavathi, Selvakumar Govindhasamy, Marcinkiewcz, Catherine A. |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Cold Spring Harbor Laboratory
2022
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8978936/ https://www.ncbi.nlm.nih.gov/pubmed/35378747 http://dx.doi.org/10.1101/2022.03.29.486282 |
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