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Body Mass Index, Interleukin-6 Signaling and Multiple Sclerosis: A Mendelian Randomization Study

OBJECTIVES: We explored whether genetically predicted increased body mass index (BMI) modulates multiple sclerosis (MS) risk through interleukin-6 (IL-6) signaling. METHODS: We performed a two-sample Mendelian randomization (MR) study using multiple genome-wide association studies (GWAS) datasets fo...

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Detalles Bibliográficos
Autores principales: Vandebergh, Marijne, Becelaere, Sara, Dubois, Bénédicte, Goris, An
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8978959/
https://www.ncbi.nlm.nih.gov/pubmed/35386698
http://dx.doi.org/10.3389/fimmu.2022.834644