Development of a gliclazide ionic liquid and its mesoporous silica particles: an effective formulation strategy to improve oral absorption properties

Ionic liquid (IL) technology provides a useful platform to enhance the oral absorption of therapeutic agents. In the present work, gliclazide (GLI), a second-generation sulfonylurea drug was transformed into an IL with tetrabutylphosphonium. The physicochemical properties of this IL were systematica...

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Detalles Bibliográficos
Autores principales: Zhou, Bijian, Teng, Dan, Li, Jinghui, Zhang, Yanhong, Qi, Minghui, Hong, Minghuang, Ren, Guo-Bin
Formato: Online Artículo Texto
Lenguaje:English
Publicado: The Royal Society of Chemistry 2022
Materias:
Chemistry
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8978969/
https://www.ncbi.nlm.nih.gov/pubmed/35425111
http://dx.doi.org/10.1039/d1ra07499g

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8978969/
https://www.ncbi.nlm.nih.gov/pubmed/35425111
http://dx.doi.org/10.1039/d1ra07499g

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