Phenylalanyl tRNA synthetase (PheRS) substrate mimics: design, synthesis, molecular dynamics and antimicrobial evaluation

Antimicrobial resistance is a very challenging medical issue and identifying novel antimicrobial targets is one of the means to overcome this challenge. Phenylalanyl tRNA synthetase (PheRS) is a promising antimicrobial target owing to its unique structure and the possibility of selectivity in the de...

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Detalles Bibliográficos
Autores principales: Noureldin, Nada A., Richards, Jennifer, Kothayer, Hend, Baraka, Mohammed M., Eladl, Sobhy M., Wootton, Mandy, Simons, Claire
Formato: Online Artículo Texto
Lenguaje:English
Publicado: The Royal Society of Chemistry 2022
Materias:
Chemistry
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8979089/
https://www.ncbi.nlm.nih.gov/pubmed/35425259
http://dx.doi.org/10.1039/d1ra06439h

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8979089/
https://www.ncbi.nlm.nih.gov/pubmed/35425259
http://dx.doi.org/10.1039/d1ra06439h

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