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The Identification of Novel CYP2D6 Variants in US Hmong: Results From Genome Sequencing and Clinical Genotyping

Objective: Hmong individuals represent a unique East Asian subpopulation in whom limited information concerning pharmacogenetic variation exists. The objectives of this study were to comprehensively characterize the highly polymorphic CYP2D6 gene in Hmong, estimate allele and phenotype frequencies a...

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Detalles Bibliográficos
Autores principales: Wen, Ya Feng, Gaedigk, Andrea, Boone, Erin C., Wang, Wendy Y., Straka, Robert J.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8979107/
https://www.ncbi.nlm.nih.gov/pubmed/35387332
http://dx.doi.org/10.3389/fphar.2022.867331