Molecular dynamics simulations and MM-GBSA reveal novel guanosine derivatives against SARS-CoV-2 RNA dependent RNA polymerase

According to the World Health Organization (WHO), SARS-CoV-2 is responsible for more than 5 M deaths and is reported in 223 countries infecting 250+ M people. Despite the current vaccination momentum, thousands of people die every day by COVID-19. Suggesting possible blockers of the viral RNA-depend...

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Detalles Bibliográficos
Autores principales: Elfiky, Abdo A., Mahran, Hanan A., Ibrahim, Ibrahim M., Ibrahim, Mohamed N., Elshemey, Wael M.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: The Royal Society of Chemistry 2022
Materias:
Chemistry
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8979119/
https://www.ncbi.nlm.nih.gov/pubmed/35425333
http://dx.doi.org/10.1039/d1ra07447d

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8979119/
https://www.ncbi.nlm.nih.gov/pubmed/35425333
http://dx.doi.org/10.1039/d1ra07447d

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