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Molecular dynamics simulations and MM-GBSA reveal novel guanosine derivatives against SARS-CoV-2 RNA dependent RNA polymerase

According to the World Health Organization (WHO), SARS-CoV-2 is responsible for more than 5 M deaths and is reported in 223 countries infecting 250+ M people. Despite the current vaccination momentum, thousands of people die every day by COVID-19. Suggesting possible blockers of the viral RNA-depend...

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Detalles Bibliográficos
Autores principales:	Elfiky, Abdo A., Mahran, Hanan A., Ibrahim, Ibrahim M., Ibrahim, Mohamed N., Elshemey, Wael M.
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	The Royal Society of Chemistry 2022
Materias:	Chemistry
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8979119/ https://www.ncbi.nlm.nih.gov/pubmed/35425333 http://dx.doi.org/10.1039/d1ra07447d

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