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Including Volume Effects in Biological Treatment Plan Optimization for Carbon Ion Therapy: Generalized Equivalent Uniform Dose-Based Objective in TRiP98

We describe a way to include biologically based objectives in plan optimization specific for carbon ion therapy, beyond the standard voxel-dose-based criteria already implemented in TRiP98, research planning software for ion beams. The aim is to account for volume effects—tissue architecture-depende...

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Detalles Bibliográficos
Autores principales: Battestini, Marco, Schwarz, Marco, Krämer, Michael, Scifoni, Emanuele
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8979211/
https://www.ncbi.nlm.nih.gov/pubmed/35387111
http://dx.doi.org/10.3389/fonc.2022.826414