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Synthesis, solid state self-assembly driven by antiparallel π⋯π stacking and {⋯H–C–C–F}(2) dimer synthons, and in vitro acetyl cholinesterase inhibition activity of phenoxy pendant isatins
A series of novel phenoxy pendant isatins PI1–12 have been synthesized in excellent yields by a simple nucleophilic substitution reaction involving isatins and 1-(2-bromoethoxy)-4-substituted benzenes, and characterized by their FT-IR, (1)H NMR, (13)C NMR and GC-MS data, and in the case of PI4 by it...
Autores principales: | , , , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
The Royal Society of Chemistry
2022
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8979220/ https://www.ncbi.nlm.nih.gov/pubmed/35425213 http://dx.doi.org/10.1039/d1ra08286h |