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Host cholesterol influences the activity of sterol biosynthesis inhibitors in Leishmania amazonensis

A significant percentage of exogenous cholesterol was found in promastigotes and amastigotes of all studied species of Leishmania, suggesting a biological role for this molecule. Previous studies have shown that promastigotes of Leishmania uptake more low-density lipoprotein (LDL) particles under ph...

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Detalles Bibliográficos
Autores principales: Andrade-Neto, Valter Viana, Manso, Pedro Paulo de Abreu, Pereira, Miria Gomes, de Cicco, Nuccia Nicole Theodoro, Atella, Georgia Corrêa, Pelajo-Machado, Marcelo, Menna-Barreto, Rubem Figueiredo Sadok, Torres-Santos, Eduardo Caio
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Instituto Oswaldo Cruz, Ministério da Saúde 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8979231/
https://www.ncbi.nlm.nih.gov/pubmed/35384972
http://dx.doi.org/10.1590/0074-02760220407