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Homogeneous antibody–angiopep 2 conjugates for effective brain targeting

Antibody-based therapy has shown great success in the treatment of many diseases, including cancers. While antibodies and antibody–drug conjugates (ADCs) have also been evaluated for central nervous system (CNS) disorders as well as brain tumors, their therapeutic efficacy can be substantially limit...

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Detalles Bibliográficos
Autores principales: Anami, Yasuaki, Xiong, Wei, Yamaguchi, Aiko, Yamazaki, Chisato M., Zhang, Ningyan, An, Zhiqiang, Tsuchikama, Kyoji
Formato: Online Artículo Texto
Lenguaje:English
Publicado: The Royal Society of Chemistry 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8979263/
https://www.ncbi.nlm.nih.gov/pubmed/35425350
http://dx.doi.org/10.1039/d1ra08131d