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Insights into the binding and covalent inhibition mechanism of PF-07321332 to SARS-CoV-2 M(pro)

The severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) has been causing the COVID-19 pandemic, resulting in several million deaths being reported. Numerous investigations have been carried out to discover a compound that can inhibit the biological activity of the SARS-CoV-2 main protease,...

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Detalles Bibliográficos
Autores principales: Ngo, Son Tung, Nguyen, Trung Hai, Tung, Nguyen Thanh, Mai, Binh Khanh
Formato: Online Artículo Texto
Lenguaje:English
Publicado: The Royal Society of Chemistry 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8979274/
https://www.ncbi.nlm.nih.gov/pubmed/35425393
http://dx.doi.org/10.1039/d1ra08752e