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Metabolism and Mass Balance in Rats Following Oral Administration of the Novel Antifibrotic Drug Fluorofenidone
OBJECTIVE: Fluorofenidone (AKF-PD) is a novel antifibrotic small-molecule compound. The purpose of this study was to investigate the metabolic and excretory pathways of AKF-PD in rats. METHODS: High-performance liquid chromatography with mass spectrometric (HPLC-MS) detection was used to analyze the...
Autores principales: | Wu, Wei, Cheng, Ze-neng |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Dove
2022
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8979420/ https://www.ncbi.nlm.nih.gov/pubmed/35386852 http://dx.doi.org/10.2147/DDDT.S346661 |
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