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Long-term stability of clopidogrel solid dispersions—Importance of in vitro dissolution test

Formulation of solid dispersions (SDs), in which the drug substance is dissolved or dispersed inside a polymer matrix, is one of the modern approaches to increase the solubility and dissolution rate of poorly soluble active pharmaceutical ingredients (APIs), such as clopidogrel. In the form of a fre...

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Detalles Bibliográficos
Autores principales: Osmanović Omerdić, Ehlimana, Alagić-Džambić, Larisa, Krstić, Marko, Pašić-Kulenović, Maja, Medarević, Đorđe, Ivković, Branka, Vasiljević, Dragana
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8979437/
https://www.ncbi.nlm.nih.gov/pubmed/35377908
http://dx.doi.org/10.1371/journal.pone.0266237