“An Intrinsic Program Determines Key Age-Associated Changes in Adaptive Immunity That Limit Response to Non-Pathogens”

As mice age their adaptive immune system changes dramatically, leading to weakened responses to newly encountered antigens and poor efficacy of vaccines. A shared pattern emerges in the aged, with both CD4 T and B cell responses requiring higher levels of pathogen recognition. Moreover, in aged germ...

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Detalles Bibliográficos
Autores principales: Swain, Susan L., Kugler-Umana, Olivia, Tonkonogy, Susan L.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2021
Materias:
Aging
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8979546/
https://www.ncbi.nlm.nih.gov/pubmed/35382063
http://dx.doi.org/10.3389/fragi.2021.701900

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8979546/
https://www.ncbi.nlm.nih.gov/pubmed/35382063
http://dx.doi.org/10.3389/fragi.2021.701900

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