Barcoded bulk QTL mapping reveals highly polygenic and epistatic architecture of complex traits in yeast

Mapping the genetic basis of complex traits is critical to uncovering the biological mechanisms that underlie disease and other phenotypes. Genome-wide association studies (GWAS) in humans and quantitative trait locus (QTL) mapping in model organisms can now explain much of the observed heritability...

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Detalles Bibliográficos
Autores principales: Nguyen Ba, Alex N, Lawrence, Katherine R, Rego-Costa, Artur, Gopalakrishnan, Shreyas, Temko, Daniel, Michor, Franziska, Desai, Michael M
Formato: Online Artículo Texto
Lenguaje:English
Publicado: eLife Sciences Publications, Ltd 2022
Materias:
Evolutionary Biology
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8979589/
https://www.ncbi.nlm.nih.gov/pubmed/35147078
http://dx.doi.org/10.7554/eLife.73983

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8979589/
https://www.ncbi.nlm.nih.gov/pubmed/35147078
http://dx.doi.org/10.7554/eLife.73983

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