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Large self-assembled clathrin lattices spontaneously disassemble without sufficient adaptor proteins

Clathrin-coated structures must assemble on cell membranes to internalize receptors, with the clathrin protein only linked to the membrane via adaptor proteins. These structures can grow surprisingly large, containing over 20 clathrin, yet they often fail to form productive vesicles, instead abortin...

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Detalles Bibliográficos
Autores principales: Guo, Si-Kao, Sodt, Alexander J., Johnson, Margaret E.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8979592/
https://www.ncbi.nlm.nih.gov/pubmed/35312692
http://dx.doi.org/10.1371/journal.pcbi.1009969