The D2R-DISC1 protein complex and associated proteins are altered in schizophrenia and normalized with antipsychotic treatment

BACKGROUND: For decades, the dopamine D2 receptor (D2R) has been known as the main target of antipsychotic medications, but the mechanism for antipsychotic effects beyond this pharmacological target remains unclear. Disrupted-in-schizophrenia 1 (DISC1) is a gene implicated in the etiology of schizop...

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Detalles Bibliográficos
Autores principales: Wang, Jijun, Su, Ping, Yang, Jian, Xu, Lihua, Yuan, Aihua, Li, Chunbo, Zhang, Tianhong, Dong, Fang, Zhou, Jingjing, Samsom, James, Wong, Albert H.C., Liu, Fang
Formato: Online Artículo Texto
Lenguaje:English
Publicado: CMA Impact Inc. 2022
Materias:
Research Paper
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8979657/
https://www.ncbi.nlm.nih.gov/pubmed/35361701
http://dx.doi.org/10.1503/jpn.210145

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8979657/
https://www.ncbi.nlm.nih.gov/pubmed/35361701
http://dx.doi.org/10.1503/jpn.210145

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