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Ageing Increases Cardiac Electrical Remodelling in Rats and Mice via NOX4/ROS/CaMKII-Mediated Calcium Signalling

OBJECTIVE: Ageing is one of the risk factors associated with cardiovascular diseases including cardiac arrhythmias and heart failure. Ageing-related cardiac dysfunction involves a complicated pathophysiological progress. Abnormal membrane voltage and Ca(2+) dynamics in aged cardiomyocytes contribute...

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Detalles Bibliográficos
Autores principales: Luo, Xian, Yu, Wendie, Liu, Zhu, Pu, Zhaoli, Liu, Ting, Li, Yangpeng, Liu, Weichao, Lei, Ming, Tan, Xiaoqiu, Chen, Tangting
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Hindawi 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8979732/
https://www.ncbi.nlm.nih.gov/pubmed/35387264
http://dx.doi.org/10.1155/2022/8538296