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Ageing Increases Cardiac Electrical Remodelling in Rats and Mice via NOX4/ROS/CaMKII-Mediated Calcium Signalling
OBJECTIVE: Ageing is one of the risk factors associated with cardiovascular diseases including cardiac arrhythmias and heart failure. Ageing-related cardiac dysfunction involves a complicated pathophysiological progress. Abnormal membrane voltage and Ca(2+) dynamics in aged cardiomyocytes contribute...
Autores principales: | Luo, Xian, Yu, Wendie, Liu, Zhu, Pu, Zhaoli, Liu, Ting, Li, Yangpeng, Liu, Weichao, Lei, Ming, Tan, Xiaoqiu, Chen, Tangting |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Hindawi
2022
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8979732/ https://www.ncbi.nlm.nih.gov/pubmed/35387264 http://dx.doi.org/10.1155/2022/8538296 |
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