Disruption of piRNA machinery by deletion of ASZ1/GASZ results in the expression of aberrant chimeric transcripts in gonocytes

In the male germline, the machinery to repress retrotransposons that threaten genomic integrity via the piRNA pathway is established in gonocytes. It has been reported that disruption of the piRNA pathway leads to activation of retrotransposons and arrests spermatogenesis before it enters the second...

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Detalles Bibliográficos
Autores principales: IKEDA, Shinya, TANAKA, Koki, OHTANI, Reiko, KANDA, Akifumi, SOTOMARU, Yusuke, KONO, Tomohiro, OBATA, Yayoi
Formato: Online Artículo Texto
Lenguaje:English
Publicado: The Society for Reproduction and Development 2022
Materias:
Original Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8979798/
https://www.ncbi.nlm.nih.gov/pubmed/35095021
http://dx.doi.org/10.1262/jrd.2021-146

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8979798/
https://www.ncbi.nlm.nih.gov/pubmed/35095021
http://dx.doi.org/10.1262/jrd.2021-146

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