Cargando…
Disruption of piRNA machinery by deletion of ASZ1/GASZ results in the expression of aberrant chimeric transcripts in gonocytes
In the male germline, the machinery to repress retrotransposons that threaten genomic integrity via the piRNA pathway is established in gonocytes. It has been reported that disruption of the piRNA pathway leads to activation of retrotransposons and arrests spermatogenesis before it enters the second...
Autores principales: | IKEDA, Shinya, TANAKA, Koki, OHTANI, Reiko, KANDA, Akifumi, SOTOMARU, Yusuke, KONO, Tomohiro, OBATA, Yayoi |
---|---|
Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
The Society for Reproduction and Development
2022
|
Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8979798/ https://www.ncbi.nlm.nih.gov/pubmed/35095021 http://dx.doi.org/10.1262/jrd.2021-146 |
Ejemplares similares
-
Daedalus and Gasz recruit Armitage to mitochondria, bringing piRNA precursors to the biogenesis machinery
por: Munafò, Marzia, et al.
Publicado: (2019) -
GASZ Is Essential for Male Meiosis and Suppression of Retrotransposon Expression in the Male Germline
por: Ma, Lang, et al.
Publicado: (2009) -
Correction: GASZ Is Essential for Male Meiosis and Suppression of Retrotransposon Expression in the Male Germline
por: Ma, Lang, et al.
Publicado: (2009) -
Telomeric TART elements target the piRNA machinery in Drosophila
por: Ellison, Christopher E., et al.
Publicado: (2020) -
Epigenetic reprogramming enables the primordial germ cell-to-gonocyte transition
por: Hill, Peter W. S., et al.
Publicado: (2018)