MicroRNA-15a-5p acts as a tumor suppressor in histiocytosis by mediating CXCL10-ERK-LIN28a-let-7 axis

Erdheim–Chester disease (ECD) is characterized by excessive production and accumulation of histiocytes within multiple tissues and organs. ECD patients harbor recurrent mutations of genes associated with the RAS/RAF/MEK/ERK signaling pathway, particularly, the BRAF(V600E) mutation. Following our pre...

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Detalles Bibliográficos
Autores principales: Weissman, Ran, Diamond, Eli L., Haroche, Julien, Durham, Benjamin H., Cohen, Fleur, Buthorn, Justin, Amoura, Zahir, Emile, Jean-François, Mazor, Roei D., Shomron, Noam, Abdel-Wahab, Omar I., Shpilberg, Ofer, Hershkovitz-Rokah, Oshrat
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2021
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8979810/
https://www.ncbi.nlm.nih.gov/pubmed/34785791
http://dx.doi.org/10.1038/s41375-021-01472-2

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8979810/
https://www.ncbi.nlm.nih.gov/pubmed/34785791
http://dx.doi.org/10.1038/s41375-021-01472-2

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