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Charge-density reduction promotes ribozyme activity in RNA–peptide coacervates via RNA fluidization and magnesium partitioning

It has long been proposed that phase-separated compartments can provide a basis for the formation of cellular precursors in prebiotic environments. However, we know very little about the properties of coacervates formed from simple peptides, their compatibility with ribozymes or their functional sig...

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Detalles Bibliográficos
Autores principales: Iglesias-Artola, Juan M., Drobot, Björn, Kar, Mrityunjoy, Fritsch, Anatol W., Mutschler, Hannes, Dora Tang, T.-Y., Kreysing, Moritz
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8979813/
https://www.ncbi.nlm.nih.gov/pubmed/35165426
http://dx.doi.org/10.1038/s41557-022-00890-8