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Charge-density reduction promotes ribozyme activity in RNA–peptide coacervates via RNA fluidization and magnesium partitioning
It has long been proposed that phase-separated compartments can provide a basis for the formation of cellular precursors in prebiotic environments. However, we know very little about the properties of coacervates formed from simple peptides, their compatibility with ribozymes or their functional sig...
Autores principales: | Iglesias-Artola, Juan M., Drobot, Björn, Kar, Mrityunjoy, Fritsch, Anatol W., Mutschler, Hannes, Dora Tang, T.-Y., Kreysing, Moritz |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Nature Publishing Group UK
2022
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8979813/ https://www.ncbi.nlm.nih.gov/pubmed/35165426 http://dx.doi.org/10.1038/s41557-022-00890-8 |
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