Protective Effects of a synthetic glycosaminoglycan mimetic (OTR4132) in a rat immunotoxic lesion model of septohippocampal cholinergic degeneration

Using a partial hippocampal cholinergic denervation model, we assessed the effects of the RGTA(®) named OTR4132, a synthetic heparan-mimetic biopolymer with neuroprotective/neurotrophic properties. Long-Evans male rats were injected with the cholinergic immunotoxin 192 IgG-saporin into the medial se...

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Detalles Bibliográficos
Autores principales: Pereira, Patricia Marques, Papy-Garcia, Dulce, Barritault, Denis, Chiappini, Franck, Jackisch, Rolf, Schimchowitsch, Sarah, Cassel, Jean-Christophe
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Springer US 2022
Materias:
Original Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8979900/
https://www.ncbi.nlm.nih.gov/pubmed/35254602
http://dx.doi.org/10.1007/s10719-022-10047-x

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8979900/
https://www.ncbi.nlm.nih.gov/pubmed/35254602
http://dx.doi.org/10.1007/s10719-022-10047-x

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