Aβ/tau oligomer interplay at human synapses supports shifting therapeutic targets for Alzheimer’s disease

BACKGROUND: Alzheimer’s disease (AD) is characterized by progressive cognitive decline due to accumulating synaptic insults by toxic oligomers of amyloid beta (AβO) and tau (TauO). There is growing consensus that preventing these oligomers from interacting with synapses might be an effective approac...

Descripción completa

Detalles Bibliográficos
Autores principales: Marcatti, Michela, Fracassi, Anna, Montalbano, Mauro, Natarajan, Chandramouli, Krishnan, Balaji, Kayed, Rakez, Taglialatela, Giulio
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Springer International Publishing 2022
Materias:
Original Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8979934/
https://www.ncbi.nlm.nih.gov/pubmed/35377002
http://dx.doi.org/10.1007/s00018-022-04255-9

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8979934/
https://www.ncbi.nlm.nih.gov/pubmed/35377002
http://dx.doi.org/10.1007/s00018-022-04255-9

Ejemplares similares