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Direct observation of chaperone-modulated talin mechanics with single-molecule resolution

Talin as a critical focal adhesion mechanosensor exhibits force-dependent folding dynamics and concurrent interactions. Being a cytoplasmic protein, talin also might interact with several cytosolic chaperones; however, the roles of chaperones in talin mechanics remain elusive. To address this questi...

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Detalles Bibliográficos
Autores principales: Chakraborty, Soham, Chaudhuri, Deep, Banerjee, Souradeep, Bhatt, Madhu, Haldar, Shubhasis
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8979947/
https://www.ncbi.nlm.nih.gov/pubmed/35379917
http://dx.doi.org/10.1038/s42003-022-03258-3