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Ensemble of nucleic acid absolute quantitation modules for copy number variation detection and RNA profiling

Current gold standard for absolute quantitation of a specific DNA sequence is droplet digital PCR (ddPCR), which has been applied to copy number variation (CNV) detection. However, the number of quantitation modules in ddPCR is limited by fluorescence channels, which thus limits the CNV sensitivity...

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Detalles Bibliográficos
Autores principales: Wu, Lucia Ruojia, Dai, Peng, Wang, Michael Xiangjiang, Chen, Sherry Xi, Cohen, Evan N., Jayachandran, Gitanjali, Zhang, Jinny Xuemeng, Serrano, Angela V., Xie, Nina Guanyi, Ueno, Naoto T., Reuben, James M., Barcenas, Carlos H., Zhang, David Yu
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8979981/
https://www.ncbi.nlm.nih.gov/pubmed/35379811
http://dx.doi.org/10.1038/s41467-022-29487-y