HSP70 attenuates compression-induced apoptosis of nucleus pulposus cells by suppressing mitochondrial fission via upregulating the expression of SIRT3

Compression-induced apoptosis of nucleus pulposus (NP) cells plays a pivotal role in the pathogenesis of intervertebral disc degeneration (IVDD). Recent studies have shown that the dysregulation of mitochondrial fission and fusion is implicated in the pathogenesis of a variety of diseases. However,...

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Detalles Bibliográficos
Autores principales: Hu, Binwu, Wang, Peng, Zhang, Shuo, Liu, Weijian, Lv, Xiao, Shi, Deyao, Zhao, Lei, Liu, Hongjian, Wang, Baichuan, Chen, Songfeng, Shao, Zengwu
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2022
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8980024/
https://www.ncbi.nlm.nih.gov/pubmed/35338257
http://dx.doi.org/10.1038/s12276-022-00745-9

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8980024/
https://www.ncbi.nlm.nih.gov/pubmed/35338257
http://dx.doi.org/10.1038/s12276-022-00745-9

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