Opposite physiological and pathological mTORC1-mediated roles of the CB1 receptor in regulating renal tubular function

Activation of the cannabinoid-1 receptor (CB(1)R) and the mammalian target of rapamycin complex 1 (mTORC1) in the renal proximal tubular cells (RPTCs) contributes to the development of diabetic kidney disease (DKD). However, the CB(1)R/mTORC1 signaling axis in the kidney has not been described yet....

Descripción completa

Detalles Bibliográficos
Autores principales: Hinden, Liad, Ahmad, Majdoleen, Hamad, Sharleen, Nemirovski, Alina, Szanda, Gergő, Glasmacher, Sandra, Kogot-Levin, Aviram, Abramovitch, Rinat, Thorens, Bernard, Gertsch, Jürg, Leibowitz, Gil, Tam, Joseph
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2022
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8980033/
https://www.ncbi.nlm.nih.gov/pubmed/35379807
http://dx.doi.org/10.1038/s41467-022-29124-8

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8980033/
https://www.ncbi.nlm.nih.gov/pubmed/35379807
http://dx.doi.org/10.1038/s41467-022-29124-8

Ejemplares similares