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Opposite physiological and pathological mTORC1-mediated roles of the CB1 receptor in regulating renal tubular function

Activation of the cannabinoid-1 receptor (CB(1)R) and the mammalian target of rapamycin complex 1 (mTORC1) in the renal proximal tubular cells (RPTCs) contributes to the development of diabetic kidney disease (DKD). However, the CB(1)R/mTORC1 signaling axis in the kidney has not been described yet....

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Detalles Bibliográficos
Autores principales:	Hinden, Liad, Ahmad, Majdoleen, Hamad, Sharleen, Nemirovski, Alina, Szanda, Gergő, Glasmacher, Sandra, Kogot-Levin, Aviram, Abramovitch, Rinat, Thorens, Bernard, Gertsch, Jürg, Leibowitz, Gil, Tam, Joseph
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Nature Publishing Group UK 2022
Materias:	Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8980033/ https://www.ncbi.nlm.nih.gov/pubmed/35379807 http://dx.doi.org/10.1038/s41467-022-29124-8

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