Indoxyl sulfate- and P-cresol-induced monocyte adhesion and migration is mediated by integrin-linked kinase-dependent podosome formation

Cardiovascular disease is an important cause of death in patients with chronic kidney disease (CKD). Protein-bound uremic toxins, such as p-cresyl and indoxyl sulfate (IS), are poorly removed during hemodialysis, leading to vascular endothelial dysfunction and leukocyte extravasation. These processe...

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Detalles Bibliográficos
Autores principales: Campillo, Sofía, Bohorquez, Lourdes, Gutiérrez-Calabrés, Elena, García-Ayuso, Diego, Miguel, Verónica, Griera, Mercedes, Calle, Yolanda, de Frutos, Sergio, Rodríguez-Puyol, Manuel, Rodríguez-Puyol, Diego, Calleros, Laura
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2022
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8980039/
https://www.ncbi.nlm.nih.gov/pubmed/35246616
http://dx.doi.org/10.1038/s12276-022-00738-8

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8980039/
https://www.ncbi.nlm.nih.gov/pubmed/35246616
http://dx.doi.org/10.1038/s12276-022-00738-8

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