GDF-15 in tumor-derived exosomes promotes muscle atrophy via Bcl-2/caspase-3 pathway

Tumor-derived exosomes are emerging mediators of cancer cachexia, a kind of multifactorial syndrome characterized by serious loss of skeletal muscle mass and function. Our previous study had showed that microRNAs in exosomes of C26 colon tumor cells were involved in induction of muscle atrophy. Here...

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Detalles Bibliográficos
Autores principales: Zhang, Wanli, Sun, Weikuan, Gu, Xiaofan, Miao, Chunxiao, Feng, Lixing, Shen, Qiang, Liu, Xuan, Zhang, Xiongwen
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2022
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8980041/
https://www.ncbi.nlm.nih.gov/pubmed/35379793
http://dx.doi.org/10.1038/s41420-022-00972-z

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8980041/
https://www.ncbi.nlm.nih.gov/pubmed/35379793
http://dx.doi.org/10.1038/s41420-022-00972-z

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