Astrocyte plasticity in mice ensures continued endfoot coverage of cerebral blood vessels following injury and declines with age

Astrocytes extend endfeet that enwrap the vasculature, and disruptions to this association which may occur in disease coincide with breaches in blood-brain barrier (BBB) integrity. Here we investigate if focal ablation of astrocytes is sufficient to disrupt the BBB in mice. Targeted two-photon chemi...

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Detalles Bibliográficos
Autores principales: Mills, William A., Woo, AnnaLin M., Jiang, Shan, Martin, Joelle, Surendran, Dayana, Bergstresser, Matthew, Kimbrough, Ian F., Eyo, Ukpong B., Sofroniew, Michael V., Sontheimer, Harald
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2022
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8980042/
https://www.ncbi.nlm.nih.gov/pubmed/35379828
http://dx.doi.org/10.1038/s41467-022-29475-2

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8980042/
https://www.ncbi.nlm.nih.gov/pubmed/35379828
http://dx.doi.org/10.1038/s41467-022-29475-2

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