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Astrocyte plasticity in mice ensures continued endfoot coverage of cerebral blood vessels following injury and declines with age
Astrocytes extend endfeet that enwrap the vasculature, and disruptions to this association which may occur in disease coincide with breaches in blood-brain barrier (BBB) integrity. Here we investigate if focal ablation of astrocytes is sufficient to disrupt the BBB in mice. Targeted two-photon chemi...
Autores principales: | Mills, William A., Woo, AnnaLin M., Jiang, Shan, Martin, Joelle, Surendran, Dayana, Bergstresser, Matthew, Kimbrough, Ian F., Eyo, Ukpong B., Sofroniew, Michael V., Sontheimer, Harald |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Nature Publishing Group UK
2022
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8980042/ https://www.ncbi.nlm.nih.gov/pubmed/35379828 http://dx.doi.org/10.1038/s41467-022-29475-2 |
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