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Nicotinic Acid Adenine Dinucleotide Phosphate Induces Intracellular Ca(2+) Signalling and Stimulates Proliferation in Human Cardiac Mesenchymal Stromal Cells
Nicotinic acid adenine dinucleotide phosphate (NAADP) is a newly discovered second messenger that gates two pore channels 1 (TPC1) and 2 (TPC2) to elicit endo-lysosomal (EL) Ca(2+) release. NAADP-induced lysosomal Ca(2+) release may be amplified by the endoplasmic reticulum (ER) through the Ca(2+)-i...
Autores principales: | , , , , , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Frontiers Media S.A.
2022
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8980055/ https://www.ncbi.nlm.nih.gov/pubmed/35392169 http://dx.doi.org/10.3389/fcell.2022.874043 |