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RAGE-TXNIP axis drives inflammation in Alzheimer’s by targeting Aβ to mitochondria in microglia

Alzheimer’s disease (AD) is the most common form of dementia characterized by progressive memory loss and cognitive decline. Although neuroinflammation and oxidative stress are well-recognized features of AD, their correlations with the early molecular events characterizing the pathology are not yet...

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Detalles Bibliográficos
Autores principales: Sbai, Oualid, Djelloul, Mehdi, Auletta, Antonia, Ieraci, Alessandro, Vascotto, Carlo, Perrone, L.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8980056/
https://www.ncbi.nlm.nih.gov/pubmed/35379773
http://dx.doi.org/10.1038/s41419-022-04758-0