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Metabotropic glutamate receptor 5 knockout rescues obesity phenotype in a mouse model of Huntington’s disease

Obesity represents a global health problem and is characterized by metabolic dysfunctions and a low-grade chronic inflammatory state, which can increase the risk of comorbidities, such as atherosclerosis, diabetes and insulin resistance. Here we tested the hypothesis that the genetic deletion of met...

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Detalles Bibliográficos
Autores principales: Santos, Rebeca P. M., Ribeiro, Roberta, Ferreira-Vieira, Talita H., Aires, Rosaria D., de Souza, Jessica M., Oliveira, Bruna S., Lima, Anna Luiza D., de Oliveira, Antônio Carlos P., Reis, Helton J., de Miranda, Aline S., Vieira, Erica M. L., Ribeiro, Fabiola M., Vieira, Luciene B.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8980063/
https://www.ncbi.nlm.nih.gov/pubmed/35379852
http://dx.doi.org/10.1038/s41598-022-08924-4