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The PripA-TbcrA complex-centered Rab GAP cascade facilitates macropinosome maturation in Dictyostelium

Macropinocytosis, an evolutionarily conserved mechanism mediating nonspecific bulk uptake of extracellular fluid, has been ascribed diverse functions. How nascent macropinosomes mature after internalization remains largely unknown. By searching for proteins that localize on macropinosomes during the...

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Detalles Bibliográficos
Autores principales: Tu, Hui, Wang, Zhimeng, Yuan, Ye, Miao, Xilin, Li, Dong, Guo, Hu, Yang, Yihong, Cai, Huaqing
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8980073/
https://www.ncbi.nlm.nih.gov/pubmed/35379834
http://dx.doi.org/10.1038/s41467-022-29503-1