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A genome-wide association study of radiotherapy induced toxicity in head and neck cancer patients identifies a susceptibility locus associated with mucositis

PURPOSE: A two-stage genome-wide association study was carried out in head and neck cancer (HNC) patients aiming to identify genetic variants associated with either specific radiotherapy-induced (RT) toxicity endpoints or a general proneness to develop toxicity after RT. MATERIALS AND METHODS: The a...

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Detalles Bibliográficos
Autores principales: Schack, Line M. H., Naderi, Elnaz, Fachal, Laura, Dorling, Leila, Luccarini, Craig, Dunning, Alison M., Ong, Enya H. W., Chua, Melvin L. K., Langendijk, Johannes A., Alizadeh, Behrooz Z., Overgaard, Jens, Eriksen, Jesper Grau, Andreassen, Christian Nicolaj, Alsner, Jan
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8980077/
https://www.ncbi.nlm.nih.gov/pubmed/35039627
http://dx.doi.org/10.1038/s41416-021-01670-w