Sirt6 reprograms myofibers to oxidative type through CREB-dependent Sox6 suppression

Expanding the exercise capacity of skeletal muscle is an emerging strategy to combat obesity-related metabolic diseases and this can be achieved by shifting skeletal muscle fibers toward slow-twitch oxidative type. Here, we report that Sirt6, an anti-aging histone deacetylase, is critical in regulat...

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Detalles Bibliográficos
Autores principales: Song, Mi-Young, Han, Chang Yeob, Moon, Young Jae, Lee, Ju Hyung, Bae, Eun Ju, Park, Byung-Hyun
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2022
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8980083/
https://www.ncbi.nlm.nih.gov/pubmed/35379817
http://dx.doi.org/10.1038/s41467-022-29472-5

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8980083/
https://www.ncbi.nlm.nih.gov/pubmed/35379817
http://dx.doi.org/10.1038/s41467-022-29472-5

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