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Extracellular HMGB1 Impairs Macrophage-Mediated Efferocytosis by Suppressing the Rab43-Controlled Cell Surface Transport of CD91

High-mobility group box 1 (HMGB1) protein can impair phagocyte function by suppressing the macrophage-mediated clearance of apoptotic cells (ACs), thereby delaying inflammation resolution in the lungs and allowing the progression of acute lung injury (ALI) and acute respiratory distress syndrome (AR...

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Detalles Bibliográficos
Autores principales: Wang, Yao, Zhang, Wen, Xu, Yu, Wu, Di, Gao, Zhan, Zhou, Jianchun, Qian, Hang, He, Binfeng, Wang, Guansong
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8980266/
https://www.ncbi.nlm.nih.gov/pubmed/35392093
http://dx.doi.org/10.3389/fimmu.2022.767630