Oxytocin exerts harmful cardiac repolarization prolonging effects in drug-induced LQTS

BACKGROUND: Oxytocin is used therapeutically in psychiatric patients. Many of these also receive anti-depressant or anti-psychotic drugs causing acquired long-QT-syndrome (LQTS) by blocking HERG/I(Kr). We previously identified an oxytocin-induced QT-prolongation in LQT2 rabbits, indicating potential...

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Detalles Bibliográficos
Autores principales: Kreifels, Paul, Bodi, Ilona, Hornyik, Tibor, Franke, Gerlind, Perez-Feliz, Stefanie, Lewetag, R., Moss, Robin, Castiglione, Alessandro, Ziupa, David, Zehender, Manfred, Brunner, Michael, Bode, Christoph, Odening, Katja E.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Elsevier 2022
Materias:
Original Paper
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8980310/
https://www.ncbi.nlm.nih.gov/pubmed/35391783
http://dx.doi.org/10.1016/j.ijcha.2022.101001

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8980310/
https://www.ncbi.nlm.nih.gov/pubmed/35391783
http://dx.doi.org/10.1016/j.ijcha.2022.101001

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