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Identification of cis-regulatory modules for adeno-associated virus-based cell-type-specific targeting in the retina and brain
Adeno-associated viruses (AAVs) targeting specific cell types are powerful tools for studying distinct cell types in the central nervous system (CNS). Cis-regulatory modules (CRMs), e.g., enhancers, are highly cell-type-specific and can be integrated into AAVs to render cell type specificity. Chroma...
Autores principales: | , , , , , , , , , , , , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
American Society for Biochemistry and Molecular Biology
2022
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8980332/ https://www.ncbi.nlm.nih.gov/pubmed/35148987 http://dx.doi.org/10.1016/j.jbc.2022.101674 |