Identification of cis-regulatory modules for adeno-associated virus-based cell-type-specific targeting in the retina and brain

Adeno-associated viruses (AAVs) targeting specific cell types are powerful tools for studying distinct cell types in the central nervous system (CNS). Cis-regulatory modules (CRMs), e.g., enhancers, are highly cell-type-specific and can be integrated into AAVs to render cell type specificity. Chroma...

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Detalles Bibliográficos
Autores principales: Lin, Cheng-Hui, Sun, Yue, Chan, Candace S.Y., Wu, Man-Ru, Gu, Lei, Davis, Alexander E., Gu, Baokun, Zhang, Wenlin, Tanasa, Bogdan, Zhong, Lei R., Emerson, Mark M., Chen, Lu, Ding, Jun B., Wang, Sui
Formato: Online Artículo Texto
Lenguaje:English
Publicado: American Society for Biochemistry and Molecular Biology 2022
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8980332/
https://www.ncbi.nlm.nih.gov/pubmed/35148987
http://dx.doi.org/10.1016/j.jbc.2022.101674

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