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Immunosuppression by piperine as a regulator of the NLRP3 inflammasome through MAPK/NF-κB in monosodium urate-induced rat gouty arthritis
BACKGROUND AND AIM: Gouty arthritis is a metabolic disorder involving monosodium urate (MSU) crystal deposition as a key initiator of acute inflammation. Dysregulation of the nucleotide-binding oligomerization domain, leucine-rich repeat, and pyrin domain-containing protein 3 (NLRP3) inflammasome is...
Autores principales: | , , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Veterinary World
2022
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Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8980401/ https://www.ncbi.nlm.nih.gov/pubmed/35400961 http://dx.doi.org/10.14202/vetworld.2022.288-298 |